お手上げ

おてあげ

being done for, giving up, being in a hopeless situation, not knowing what to do, being brought to one's knees, throwing up (one's) hands

JLPT N1

Details

この問題はお手上げだ

I'm at my wit's end with this problem

問題が難しすぎて、私はすっかりお手上げだった。

The problem was so difficult that I was completely at a loss.

機械の故障の原因が分からず、技術者もお手上げの様子だ。

The cause of the machine's breakdown was unknown, and even the engineer seemed stumped.